PRELIMINARY STUDIES FOR IN VIVO APPLICATION OF SURFACE TREATED Ti6Al7Nb PROSTHESES
نویسندگان
چکیده
The aim of this paper is to compare the bioactive behavior generated by two different surface treatments on Ti-6Al-7Nb previous to the implant in the animal knee. One of the treatments consists in soak the sample with NaOH and followed by a subsequent heat treatment. The other treatment consists in immersion for 19 days in a SBF solution with additional PAW1 biovitroceramic (particles under 20 μm) content at 36 oC. After a long exposure (more than 100 days) of the samples to a simulated body fluid, the surfaces were investigated to clarify what bioactive structure forms on the alloy and how it changes in the body’s environment. A knee plate was design for the samples of Ti-6Al-7Nb.
منابع مشابه
Epidemiological studies of hepatitis B: Preliminary report on adjuvant potential of Calotropis gigantea and Ficus religiosa against hepatitis B vaccine containing surface antigen
Background and aims: The frequency of chronic hepatitis B virus infection varies totally in different part of the world but it could be categorized as high, intermediate and low endimicity. In this regard, development of safe and effective vaccines against infectious diseases especially hepatitis B virus that are still required for emerging new pathogens, re-emerging old pathog...
متن کاملProduction and evaluation of [67Ga]-DTPA-Rituximab
Background: In order to obtain an anti-CD20 conjugate to be used in future therapeutic studies with therapeutic radioisotopes, 67Ga-labeled antibody was prepared as a model of metal chelated immunoconjugate for preliminary dosimetric and biodistribution studies. Materials and Methods: Rituximab was labeled with [67Ga]-gallium chloride after residulation with freshly prepared cyclic DTP...
متن کاملIn Vivo Study of Diethylstilbestrol Teratogenicity on Mouse Embryo
Diethylstilbestrol (DES) was widely used in the past, as the morning after contraception, but its application became extremely limited due to several complications including delayed clear cell adenocarcinoma in female infants. However, the use of DES increased during the past decade for hormone replacement therapy. The aim of this study was to investigate possible teratogenicity of this...
متن کاملEnhanced Transdermal Delivery of Granisetron by Using Iontophoresis
The purpose of the present study was to explore the passive and electrically assisted transdermal transport of Granisetron hydrochloride (GRA) in solution and gel formulation through iontophoresis and also the feasibility of delivering therapeutic amounts of drug for the treatment of chemotherapy-induced nausea and vomiting. In this study, iontophoretic permeation of GRA through guinea pig...
متن کاملApplication of FITC for detecting the binding of antiangiogenic peptide to HUVECs
Angiogenesis is the generation of new blood vessels from the existing vasculature. The angiogenic programme requires the degradation of the basement membrane, endothelial cell migration and invasion of the extracellular matrix, with endothelial cell proliferation and capillary lumen formation before maturation and stabilization of the new vasculature. Angiogenesis is dependent on a delicate equ...
متن کامل